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Antimicrobial resistance in N. gonorrhoeae remains an important challenge to controlling gonorrhea; gonococcal strains may be resistant to penicillins, tetracyclines, spectinomycin, and fluoroquinolones. Resistance to CDC-recommended doses of ciprofloxacin and ofloxacin exceeds 40% in some Asian countries (World Health Organization (WHO) Western Pacific Region Gonococcal Antimicrobial Susceptibility Programme (GASP) Report; 2000).

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